Medical Researches
Moderately Effective
Based on 24 Researches
We investigated how Lactobacillus rhamnosus Lcr35, contained in the GYNOPHILUS product, can combat yeast infections like Candida. This study showed that the product’s formulation, enhanced by sodium thiosulfate, improves its ability to kill yeast cells.
Remarkably, after 48 hours of co-culturing, the yeast’s viability dropped to zero. The presence of odor-active sulfur compounds, specifically S-methyl thioacetate, was linked to this antifungal effect.
Interestingly, achieving the full antifungal impact relies on these sulfur components.
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Lactobacillus rhamnosus shows promiseAnticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation.
High relevance for Candida treatment.
We examined the effectiveness of various Lactobacillus strains, particularly Lactobacillus rhamnosus, against yeast infections caused by Candida. Through our analysis, we found that live probiotic cells and their cell-free supernatants showed strong anticandidal activity.
Notably, L. rhamnosus SD11 was especially effective, particularly when supplemented with prebiotics like mangosteen, leading to improved growth and metabolic activity. This suggests that combining probiotics and prebiotics might be a promising alternative treatment for Candida infections.
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Probiotic shows potential against fungusLactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection in the invertebrate model Caenorhabditis elegans: First mechanistic insights.
Relevant for antifungal strategies
We investigated the effectiveness of Lactobacillus rhamnosus Lcr35® against Candida albicans using lab models. The study showed that this probiotic significantly reduced fungal growth and adhesion in cell cultures.
In the nematode model, it helped improve worm survival rates, even against detectable yeast. The probiotic appeared to suppress the fungus's virulence while also activating the worm's immune responses. Overall, the findings suggest that Lcr35® could be a promising strategy for combatting yeast infections.
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This study examined how Lactobacillus rhamnosus could impact the development of yeast infections, specifically candidiasis. By using immunosuppressed mice, we created various groups to see if taking this probiotic before or during Candida exposure made a difference.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
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Potential ally against Candida infectionsImmunomodulatory effects and anti-Candida activity of lactobacilli in macrophages and in invertebrate model of Galleria mellonella.
Highly relevant to fungal treatment
We explored how Lactobacillus rhamnosus (LR) can aid in fighting Candida infections. The study tested LR and other lactobacilli in both mouse macrophages and Galleria mellonella larvae.
Results showed that LR significantly boosted immune responses and enhanced larvae survival against Candida. In particular, it reduced yeast counts, showcasing its potential as an adjunct treatment for managing yeast infections.
Ultimately, LR stood out for its anti-Candida effects, making it a promising ally against these tough fungal threats.
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User Reviews
Excellent
Based on 143 Reviews
The unpleasant odour I had experienced for decades vanished overnight after taking this supplement. No more itching; it's truly a miracle for my confidence!
Excellent for bladder infections! I had recurrent bladder infections for years, trying everything from cranberry juice to D-mannose. Desperate, I bought these probiotics, and they really saved me! I've used them for over eight years, only experiencing one infection when I forgot them on holiday. They genuinely work, and I highly recommend them to anyone with similar issues.
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My friend recommended this. Probiotics can reduce yeast infections in various organ systems. This product resolved my Candidiasis issue. I’ve been using it for three months and my problem is solved.
Very excellent! I’ve purchased this for the third time for gynecological infections. It works effectively for me.
I bought this and another package. The taste is acceptable, and as a vegetarian, I appreciate the vegetarian capsules. My yeast infection has not recurred for four months. I also focus on work, rest, and a healthy lifestyle for best results.